Endocrine Abstracts

In July 2016, an International Turner Syndrome Meeting was organized in Cincinnati, Ohio, USA. Today, an updated document concerning the Clinical Practice Guidelines for the Care of Girls and Women with Turner Syndrome is finalized. This document gives the summary of the evidence and expert opinions about several aspects of the treatment and follow-up of individuals with Turner syndrome. It will be published soon. In this presentation, the main conclusions and recommendations ...

Introduction: Hypertension is common in patients with Turner Syndrome (TS), and they appear to have an increased predisposition with various proposed disease related factors; sex hormone imbalance, aortopathy, increased activation of the renin-angiotensin-aldosterone system, insulin resistance, growth hormone deficiency/resistance, adverse imprinting during fetal life and renal malformations. Despite high susceptibility and unique challenges in managing hypertension in this gr...

Introduction: Cardiovascular disease is the commonest cause of death (absolute-excess-risk:41%) in Turner Syndrome (TS). Hypertension is a major risk for circulatory-disease (up to 60%) and a key modifiable-risk factor of aortopathy, ischemic heart disease and stroke in TS. There is no current consensus for hypertension diagnosis/management in TS.Methods: Retrospective multi-centre observational study of patients aged &#...